Niels H Skotte

Affiliations

Centre for Molecular Medicine and Therapeutics (CMMT), Department of Medical Genetics, University of British Columbia, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada.

Publications (11)

Dysregulated COMT Expression in Fragile X Syndrome.

Neuromolecular medicine

Avec: Kagistia Hana Utami , Nur Amirah Binte Muhammed Yusof , Marta Garcia-Miralles , Niels Henning Skotte , Srikanth Nama , Prabha Sampath , Sarah R Langley , Mahmoud A Pouladi

Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound.

Cell chemical biology

Avec: Dagmar E Ehrnhoefer , Niels H Skotte , Jeanette Reinshagen , Xiaofan Qiu , Björn Windshügel , Priyadarshini Jaishankar , Safia Ladha , Olga Petina , Mehdi Khankischpur , Yen T N Nguyen , Nicholas S Caron , Adelia Razeto , Matthias Meyer Zu Rheda , Yu Deng , Khuong T Huynh , Ilka Wittig , Philip Gribbon , Adam R Renslo , Detlef Geffken , Sheraz Gul , Michael R Hayden

Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease.

Cell death & disease

Avec: Jens V Andersen , Niels H Skotte , Sofie K Christensen , Filip S Polli , Mohammad Shabani , Kia H Markussen , Henriette Haukedal , Emil W Westi , Marta Diaz-delCastillo , Ramon C Sun , Kristi A Kohlmeier , Arne Schousboe , Matthew S Gentry , Heikki Tanila , Kristine K Freude , Blanca I Aldana , Matthias Mann , Helle S Waagepetersen

Deletion of CaMKIIα disrupts glucose metabolism, glutamate uptake, and synaptic energetics in the cerebral cortex.

Journal of neurochemistry

Avec: Jens V Andersen , Emil W Westi , Nane Griem-Krey , Niels H Skotte , Arne Schousboe , Blanca I Aldana , Petrine Wellendorph

Compromised IGF signaling causes caspase-6 activation in Huntington disease.

Experimental neurology

Avec: Niels Henning Skotte , Mahmoud A Pouladi , Dagmar E Ehrnhoefer , Katie Huynh , Xiaofan Qiu , Signe Marie Borch Nielsen , Troels Tolstrup Nielsen , Anne Nørremølle , Michael R Hayden

Enhanced cerebral branched-chain amino acid metabolism in R6/2 mouse model of Huntington's disease.

Cellular and molecular life sciences : CMLS

Avec: Jens V Andersen , Niels H Skotte , Blanca I Aldana , Anne Nørremølle , Helle S Waagepetersen

Functional Differences between Synaptic Mitochondria from the Striatum and the Cerebral Cortex.

Neuroscience

Avec: Maria Hvidberg Petersen , Cecilie Wennemoes Willert , Jens Velde Andersen , Helle Sønderby Waagepetersen , Niels Henning Skotte , Anne Nørremølle

Progressive Mitochondrial Dysfunction of Striatal Synapses in R6/2 Mouse Model of Huntington's Disease.

Journal of Huntington's disease

Avec: Maria Hvidberg Petersen , Cecilie Wennemoes Willert , Jens Velde Andersen , Mette Madsen , Helle Sønderby Waagepetersen , Niels Henning Skotte , Anne Nørremølle

Integrative Analysis Identifies Key Molecular Signatures Underlying Neurodevelopmental Deficits in Fragile X Syndrome.

Biological psychiatry

Avec: Kagistia Hana Utami , Niels H Skotte , Ana R Colaço , Nur Amirah Binte Mohammad Yusof , Bernice Sim , Xin Yi Yeo , Han-Gyu Bae , Marta Garcia-Miralles , Carola I Radulescu , Qiyu Chen , Georgia Chaldaiopoulou , Herty Liany , Srikanth Nama , Ulla-Kaisa A Peteri , Prabha Sampath , Maija L Castrén , Sangyong Jung , Matthias Mann , Mahmoud A Pouladi

Characterising the RNA-binding protein atlas of the mammalian brain uncovers RBM5 misregulation in mouse models of Huntington's disease.

Nature communications

Avec: Meeli Mullari , Nicolas Fossat , Niels H Skotte , Andrea Asenjo-Martinez , David T Humphreys , Jens Bukh , Agnete Kirkeby , Troels K H Scheel , Michael L Nielsen

Deficient brain GABA metabolism leads to widespread impairments of astrocyte and oligodendrocyte function.

Glia

Avec: Jens V Andersen , Oana C Marian , Filippa L Qvist , Emil W Westi , Blanca I Aldana , Arne Schousboe , Anthony S Don , Niels H Skotte , Petrine Wellendorph

Réseau de co-auteurs

Niels Henning Skotte 4 collaborations

Jens V Andersen 4 collaborations

Blanca I Aldana 4 collaborations

Anne Nørremølle 4 collaborations

Mahmoud A Pouladi 3 collaborations

Emil W Westi 3 collaborations

Arne Schousboe 3 collaborations

Kagistia Hana Utami 2 collaborations

Marta Garcia-Miralles 2 collaborations

Srikanth Nama 2 collaborations

Prabha Sampath 2 collaborations

Dagmar E Ehrnhoefer 2 collaborations

Xiaofan Qiu 2 collaborations

Michael R Hayden 2 collaborations

Matthias Mann 2 collaborations

Helle S Waagepetersen 2 collaborations

Petrine Wellendorph 2 collaborations

Maria Hvidberg Petersen 2 collaborations

Cecilie Wennemoes Willert 2 collaborations

Jens Velde Andersen 2 collaborations

Helle Sønderby Waagepetersen 2 collaborations

Nur Amirah Binte Muhammed Yusof 1 collaboration

Sarah R Langley 1 collaboration

Jeanette Reinshagen 1 collaboration

Björn Windshügel 1 collaboration

Priyadarshini Jaishankar 1 collaboration

Safia Ladha 1 collaboration

Olga Petina 1 collaboration

Mehdi Khankischpur 1 collaboration

Yen T N Nguyen 1 collaboration

Nicholas S Caron 1 collaboration

Adelia Razeto 1 collaboration

Matthias Meyer Zu Rheda 1 collaboration

Yu Deng 1 collaboration

Khuong T Huynh 1 collaboration

Ilka Wittig 1 collaboration

Philip Gribbon 1 collaboration

Adam R Renslo 1 collaboration

Detlef Geffken 1 collaboration

Sheraz Gul 1 collaboration

Sofie K Christensen 1 collaboration

Filip S Polli 1 collaboration

Mohammad Shabani 1 collaboration

Kia H Markussen 1 collaboration

Henriette Haukedal 1 collaboration

Marta Diaz-delCastillo 1 collaboration

Ramon C Sun 1 collaboration

Kristi A Kohlmeier 1 collaboration

Matthew S Gentry 1 collaboration

Heikki Tanila 1 collaboration

Kristine K Freude 1 collaboration

Nane Griem-Krey 1 collaboration

Katie Huynh 1 collaboration

Signe Marie Borch Nielsen 1 collaboration

Troels Tolstrup Nielsen 1 collaboration

Mette Madsen 1 collaboration

Ana R Colaço 1 collaboration

Nur Amirah Binte Mohammad Yusof 1 collaboration

Bernice Sim 1 collaboration

Xin Yi Yeo 1 collaboration

Han-Gyu Bae 1 collaboration

Carola I Radulescu 1 collaboration

Qiyu Chen 1 collaboration

Georgia Chaldaiopoulou 1 collaboration

Herty Liany 1 collaboration

Ulla-Kaisa A Peteri 1 collaboration

Maija L Castrén 1 collaboration

Sangyong Jung 1 collaboration

Meeli Mullari 1 collaboration

Nicolas Fossat 1 collaboration

Andrea Asenjo-Martinez 1 collaboration

David T Humphreys 1 collaboration

Jens Bukh 1 collaboration

Agnete Kirkeby 1 collaboration

Troels K H Scheel 1 collaboration

Michael L Nielsen 1 collaboration

Oana C Marian 1 collaboration

Filippa L Qvist 1 collaboration

Anthony S Don 1 collaboration